hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20090630/iprscan-20090630-15380429/chunk_1/iprscan-20090630-15380429.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: af12940s1 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF00621.11.fs RhoGEF domain 138.1 1.3e-40 1 PF00621.11.ls RhoGEF domain 139.9 6.5e-39 1 PF00169.19.fs PH domain 55.6 1.8e-16 1 PF00169.19.ls PH domain 57.7 3.6e-14 1 PF00018.18.fs SH3 domain 49.3 1.1e-12 1 PF00018.18.ls SH3 domain 51.2 3.2e-12 1 PF07653.7.fs Variant SH3 domain 28.3 1.6e-07 1 PF07653.7.ls Variant SH3 domain 29.3 1.3e-05 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00018.18.ls 1/1 823 877 .. 1 59 [] 51.2 3.2e-12 PF00018.18.fs 1/1 823 877 .. 1 59 [] 49.3 1.1e-12 PF07653.7.ls 1/1 824 877 .. 1 69 [] 29.3 1.3e-05 PF07653.7.fs 1/1 830 877 .. 7 69 .] 28.3 1.6e-07 PF00621.11.fs 1/1 917 1096 .. 1 207 [] 138.1 1.3e-40 PF00621.11.ls 1/1 917 1096 .. 1 207 [] 139.9 6.5e-39 PF00169.19.fs 1/1 1129 1234 .. 1 92 [] 55.6 1.8e-16 PF00169.19.ls 1/1 1129 1234 .. 1 92 [] 57.7 3.6e-14 Alignments of top-scoring domains: PF00018.18.ls: domain 1 of 1, from 823 to 877: score 51.2, E = 3.2e-12 *->kkvvALYDYearesdELsFkkGDvitvleksddpgWWkgrlkgtgGk + AL D + ++++EL Fk GDvi+vle s+ +WW gr+ +k af12940s1 823 VCAEALWDHVTMDDQELGFKAGDVIQVLEASNK-DWWWGRSE---DK 865 eGliPsNYVepv<-* e ++P+++V++ af12940s1 866 EAWFPASFVRLR 877 PF00018.18.fs: domain 1 of 1, from 823 to 877: score 49.3, E = 1.1e-12 *->kkvvALYDYearesdELsFkkGDvitvleksddpgWWkgrlkgtgGk + AL D + ++++EL Fk GDvi+vle s+ +WW gr+ +k af12940s1 823 VCAEALWDHVTMDDQELGFKAGDVIQVLEASNK-DWWWGRSE---DK 865 eGliPsNYVepv<-* e ++P+++V++ af12940s1 866 EAWFPASFVRLR 877 PF07653.7.ls: domain 1 of 1, from 824 to 877: score 29.3, E = 1.3e-05 *->ygraiedyvaAtdknenleeeeLslkkGdvvkVidvggskdddgwwe + a+ d+v d +e L +k+Gdv+ V+ + ++ +ww+ af12940s1 824 CAEALWDHVT-MDDQE------LGFKAGDVIQVL----EASNKDWWW 859 geslggGrrrRGlvPssaveel<-* g+s ++++ ++P+s+v+ af12940s1 860 GRS-EDKEA---WFPASFVRLR 877 PF07653.7.fs: domain 1 of 1, from 830 to 877: score 28.3, E = 1.6e-07 *->dyvaAtdknenleeeeLslkkGdvvkVidvggskdddgwwegeslgg d+v d +e L +k+Gdv+ V+ + ++ +ww+g+s + af12940s1 830 DHVT-MDDQE------LGFKAGDVIQVL----EASNKDWWWGRS-ED 864 GrrrRGlvPssaveel<-* +++ ++P+s+v+ af12940s1 865 KEA---WFPASFVRLR 877 PF00621.11.fs: domain 1 of 1, from 917 to 1096: score 138.1, E = 1.3e-40 *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF v++E++ TE++Y+++L+++ +y ++ r+ + +t ++ tiF af12940s1 917 VIREIMDTERVYIKHLRDICEGYIRQCRK--HTG--MFTVAQLATIF 959 sNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFlelk +Niediy+f+r FLk Le+ + ep+ + +G++Fl+ af12940s1 960 GNIEDIYKFQRKFLK-DLEKQYNKE----------EPHLSEIGSCFLQN- 997 aeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd e + +Y eYc+n+p A l+ l + + F+e + +++ + af12940s1 998 QEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQMID----- 1042 davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkkalda ++ +Ll Pvq i++YpL L eLLk+t ++ ++ + k+a++a af12940s1 1043 ----IAIDGFLLTPVQKICKYPLQLAELLKYTTQ--EHGDYSNIKAAYEA 1086 lqdlaksiNe<-* ++++a iNe af12940s1 1087 MKNVACLINE 1096 PF00621.11.ls: domain 1 of 1, from 917 to 1096: score 139.9, E = 6.5e-39 *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF v++E++ TE++Y+++L+++ +y ++ r+ + +t ++ tiF af12940s1 917 VIREIMDTERVYIKHLRDICEGYIRQCRK--HTG--MFTVAQLATIF 959 sNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFlelk +Niediy+f+r FLk Le+ + ep+ + +G++Fl+ af12940s1 960 GNIEDIYKFQRKFLK-DLEKQYNKE----------EPHLSEIGSCFLQN- 997 aeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd e + +Y eYc+n+p A l+ l + + F+e + +++ + af12940s1 998 QEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQMID----- 1042 davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkkalda ++ +Ll Pvq i++YpL L eLLk+t ++ ++ + k+a++a af12940s1 1043 ----IAIDGFLLTPVQKICKYPLQLAELLKYTTQ--EHGDYSNIKAAYEA 1086 lqdlaksiNe<-* ++++a iNe af12940s1 1087 MKNVACLINE 1096 PF00169.19.fs: domain 1 of 1, from 1129 to 1234: score 55.6, E = 1.8e-16 *->vikeGwLlkkggkkswkkRyfvLfddvLlyykdkk.....kkpkgsi +i++G+L+k ++ ++ ++R f+Lfd +L+ +k++ +++ +kg + af12940s1 1129 LIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLlrrdmLYYKGRL 1175 pLsgiqvtkvpdn.......krkncFeirt.dr.etlllqaeseeerkeW ++++++++++ d+++++ + kn+F++++++ +e++l++a+ +e++ +W af12940s1 1176 DMDEMELVDLGDGrdkdcnlSVKNAFKLVSrTTdEVYLFCAKKQEDKARW 1225 vkaiqsair<-* ++a+ + r af12940s1 1226 LQACADERR 1234 PF00169.19.ls: domain 1 of 1, from 1129 to 1234: score 57.7, E = 3.6e-14 *->vikeGwLlkkggkkswkkRyfvLfddvLlyykdkk.....kkpkgsi +i++G+L+k ++ ++ ++R f+Lfd +L+ +k++ +++ +kg + af12940s1 1129 LIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLlrrdmLYYKGRL 1175 pLsgiqvtkvpdn.......krkncFeirt.dr.etlllqaeseeerkeW ++++++++++ d+++++ + kn+F++++++ +e++l++a+ +e++ +W af12940s1 1176 DMDEMELVDLGDGrdkdcnlSVKNAFKLVSrTTdEVYLFCAKKQEDKARW 1225 vkaiqsair<-* ++a+ + r af12940s1 1226 LQACADERR 1234 //