hmmpfam - search one or more sequences against HMM database HMMER 2.3.2 (Oct 2003) Copyright (C) 1992-2003 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /db/iprscan/data/Pfam.bin Sequence file: /db/iprscan/tmp/20080806/iprscan-20080806-21125964/chunk_1/iprscan-20080806-21125964.nocrc - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: ah02979 Accession: [none] Description: [none] Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- PF07714.7.ls Protein tyrosine kinase 532.0 6.1e-157 1 PF07714.7.fs Protein tyrosine kinase 530.1 2.2e-156 1 PF08919.1.ls F-actin binding 478.2 9.2e-141 1 PF08919.1.fs F-actin binding 476.2 3.6e-140 1 PF00069.15.ls Protein kinase domain 180.9 2.9e-51 1 PF00069.15.fs Protein kinase domain 179.1 9.2e-51 1 PF00017.14.fs SH2 domain 123.6 8e-42 1 PF00017.14.ls SH2 domain 125.6 1.3e-34 1 PF00018.18.ls SH3 domain 74.3 3.6e-19 1 PF00018.18.fs SH3 domain 72.4 5.1e-19 1 PF07653.7.fs Variant SH3 domain 38.8 1.6e-10 1 PF07653.7.ls Variant SH3 domain 40.5 5.2e-09 1 PF08239.2.fs Bacterial SH3 domain 16.7 0.00048 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- PF00018.18.ls 1/1 101 156 .. 1 59 [] 74.3 3.6e-19 PF00018.18.fs 1/1 101 156 .. 1 59 [] 72.4 5.1e-19 PF07653.7.ls 1/1 102 156 .. 1 69 [] 40.5 5.2e-09 PF07653.7.fs 1/1 102 156 .. 1 69 [] 38.8 1.6e-10 PF08239.2.fs 1/1 118 154 .. 18 55 .] 16.7 0.00048 PF00017.14.ls 1/1 164 239 .. 1 82 [] 125.6 1.3e-34 PF00017.14.fs 1/1 164 239 .. 1 82 [] 123.6 8e-42 PF07714.7.fs 1/1 279 530 .. 1 272 [] 530.1 2.2e-156 PF07714.7.ls 1/1 279 530 .. 1 272 [] 532.0 6.1e-157 PF00069.15.ls 1/1 279 530 .. 1 287 [] 180.9 2.9e-51 PF00069.15.fs 1/1 279 530 .. 1 287 [] 179.1 9.2e-51 PF08919.1.fs 1/1 990 1167 .] 1 179 [] 476.2 3.6e-140 PF08919.1.ls 1/1 990 1167 .] 1 179 [] 478.2 9.2e-141 Alignments of top-scoring domains: PF00018.18.ls: domain 1 of 1, from 101 to 156: score 74.3, E = 3.6e-19 *->kkvvALYDYearesdELsFkkGDvitvleksddpgWWkgrlkgtgGk +vALYD++a++++ Ls++kG+++ vl + +++W++++ k + ah02979 101 NLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTK---NG 144 eGliPsNYVepv<-* +G++PsNY++pv ah02979 145 QGWVPSNYITPV 156 PF00018.18.fs: domain 1 of 1, from 101 to 156: score 72.4, E = 5.1e-19 *->kkvvALYDYearesdELsFkkGDvitvleksddpgWWkgrlkgtgGk +vALYD++a++++ Ls++kG+++ vl + +++W++++ k + ah02979 101 NLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTK---NG 144 eGliPsNYVepv<-* +G++PsNY++pv ah02979 145 QGWVPSNYITPV 156 PF07653.7.ls: domain 1 of 1, from 102 to 156: score 40.5, E = 5.2e-09 *->ygraiedyvaAtdknenleeeeLslkkGdvvkVidvggskddd.gww +++a+ d+va ++ n Ls++kG++++V+ +++ +++w+ ah02979 102 LFVALYDFVA-SGDNT------LSITKGEKLRVL----GYNHNgEWC 137 egeslggGrrrRGlvPssaveel<-* e+ + ++ G+vPs+++ ++ ah02979 138 EAQT--KNGQ--GWVPSNYITPV 156 PF07653.7.fs: domain 1 of 1, from 102 to 156: score 38.8, E = 1.6e-10 *->ygraiedyvaAtdknenleeeeLslkkGdvvkVidvggskddd.gww +++a+ d+va ++ n Ls++kG++++V+ +++ +++w+ ah02979 102 LFVALYDFVA-SGDNT------LSITKGEKLRVL----GYNHNgEWC 137 egeslggGrrrRGlvPssaveel<-* e+ + ++ G+vPs+++ ++ ah02979 138 EAQT--KNGQ--GWVPSNYITPV 156 PF08239.2.fs: domain 1 of 1, from 118 to 154: score 16.7, E = 0.00048 *->qlpkGtkVtvlge.engngWykIeynGktGYVlssdYvs<-* ++ kG+k+ vlg + ng W++ + +++ G+V s+Y++ ah02979 118 SITKGEKLRVLGYnHNGE-WCEAQTKNGQGWV-PSNYIT 154 PF00017.14.ls: domain 1 of 1, from 164 to 239: score 125.6, E = 1.3e-34 *->WyhGkIsRkeAErlLlnpggkdGtFLvReSestpGdYtLSVrddgpq WyhG++sR+ AE lL + g +G+FLvReSes+pG+ ++S+r++g ah02979 164 WYHGPVSRNAAEYLLSS--GINGSFLVRESESSPGQRSISLRYEG-- 206 gdrVkHyrIqsldnggyyitggvkFssLpeLvehY<-* rV+HyrI++ +g++y++ + +F++L+eLv+h+ ah02979 207 --RVYHYRINTASDGKLYVSSESRFNTLAELVHHH 239 PF00017.14.fs: domain 1 of 1, from 164 to 239: score 123.6, E = 8e-42 *->WyhGkIsRkeAErlLlnpggkdGtFLvReSestpGdYtLSVrddgpq WyhG++sR+ AE lL + g +G+FLvReSes+pG+ ++S+r++g ah02979 164 WYHGPVSRNAAEYLLSS--GINGSFLVRESESSPGQRSISLRYEG-- 206 gdrVkHyrIqsldnggyyitggvkFssLpeLvehY<-* rV+HyrI++ +g++y++ + +F++L+eLv+h+ ah02979 207 --RVYHYRINTASDGKLYVSSESRFNTLAELVHHH 239 PF07714.7.fs: domain 1 of 1, from 279 to 530: score 530.1, E = 2.2e-156 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie +++ +kLG G++GeVy+G++k + ++VAVKtLke +++e ah02979 279 ITMKHKLGGGQYGEVYEGVWK----KYSLTVAVKTLKE-DTMEV--- 317 redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL e+Fl+EA++Mk++ +HpN+V+LlGvct+ + P yi+tE+m +G+L ah02979 318 -EEFLKEAAVMKEI-KHPNLVQLLGVCTR-EPP----FYIITEFMTYGNL 360 ldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLVs ld+Lr+ +++ ++ Ll +a+Qi+++MeYLe knf+HRDLAARNcLV+ ah02979 361 LDYLREC-NRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG 409 enlvVKIsDFGLaRdiynddyYvrkkgggklPvkWmAPEslkygkFtskS en+ VK++DFGL+R++ d+Y +++ g+k+P+kW+APEsl+y+kF++kS ah02979 410 ENHLVKVADFGLSRLM-TGDTY-TAHAGAKFPIKWTAPESLAYNKFSIKS 457 DVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPenCPdel DVW+FGVlLWEi t+G++P Ypg++ ++v+ell e++yR++rPe+CP+++ ah02979 458 DVWAFGVLLWEIATYGMSP-YPGIDLSQVYELL-EKDYRMERPEGCPEKV 505 YdlMlqCWaedPedRPtFselveeL<-* Y+lM+ CW+++P+dRP+F+e+++ + ah02979 506 YELMRACWQWNPSDRPSFAEIHQAF 530 PF07714.7.ls: domain 1 of 1, from 279 to 530: score 532.0, E = 6.1e-157 *->lklgkkLGeGaFGeVykGtlkgsgdgteikVAVKtLkeigaseeeie +++ +kLG G++GeVy+G++k + ++VAVKtLke +++e ah02979 279 ITMKHKLGGGQYGEVYEGVWK----KYSLTVAVKTLKE-DTMEV--- 317 redFlrEAsiMkklGdHpNiVrLlGvctkegePggpglyiVtEymegGdL e+Fl+EA++Mk++ +HpN+V+LlGvct+ + P yi+tE+m +G+L ah02979 318 -EEFLKEAAVMKEI-KHPNLVQLLGVCTR-EPP----FYIITEFMTYGNL 360 ldfLrkhregrpLtlkdLlsfalQiAkGMeYLesknfvHRDLAARNcLVs ld+Lr+ +++ ++ Ll +a+Qi+++MeYLe knf+HRDLAARNcLV+ ah02979 361 LDYLREC-NRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVG 409 enlvVKIsDFGLaRdiynddyYvrkkgggklPvkWmAPEslkygkFtskS en+ VK++DFGL+R++ d+Y +++ g+k+P+kW+APEsl+y+kF++kS ah02979 410 ENHLVKVADFGLSRLM-TGDTY-TAHAGAKFPIKWTAPESLAYNKFSIKS 457 DVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprPenCPdel DVW+FGVlLWEi t+G++P Ypg++ ++v+ell e++yR++rPe+CP+++ ah02979 458 DVWAFGVLLWEIATYGMSP-YPGIDLSQVYELL-EKDYRMERPEGCPEKV 505 YdlMlqCWaedPedRPtFselveeL<-* Y+lM+ CW+++P+dRP+F+e+++ + ah02979 506 YELMRACWQWNPSDRPSFAEIHQAF 530 PF00069.15.ls: domain 1 of 1, from 279 to 530: score 180.9, E = 2.9e-51 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr ++ + klG G +G+Vy++++k+++ +VAvK++k ++ + ++ ah02979 279 ITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLK--- 322 lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse E++++k+++HpN v+l++v+++++ y+++E++ G L dyl+ ah02979 323 --EAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYG----NLLDYLR- 365 trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv ++ + ++ +a+Qi +++eYL ++++iHRDL N+L+ +n ah02979 366 ECNRQEV--NAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHL 413 vdaflKiaDFGlAkkls...t.sss.lttfvGTpwYmAPEvllggngygt v K+aDFGl++++ +++++ +++ + + + APE l +n+ + ah02979 414 V----KVADFGLSRLMTgdtYtAHAgAKFP---IKWTAPESLA-YNKFSI 455 kvDvWSlGvilyellt.GkpPFsgevqdsldqlqlirkilgpplefdspe k+DvW++Gv+l+e +t G P++g d q++++ + +++ ++pe ah02979 456 KSDVWAFGVLLWEIATyGMSPYPGI-----DLSQVYELLEK-DYRMERPE 499 wdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-* ++ e +L++ c++++Ps+R++++ei q f ah02979 500 GCP-------------EKVYELMRACWQWNPSDRPSFAEIHQA--F 530 PF00069.15.fs: domain 1 of 1, from 279 to 530: score 179.1, E = 9.2e-51 *->yelleklGsGsfGtVykakhkgtgkiVAvKiikkrkekskkdktarr ++ + klG G +G+Vy++++k+++ +VAvK++k ++ + ++ ah02979 279 ITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLK--- 322 lsEiqilkrLsHpNIvrlidvfedkdhlylVlEycegGLrvldLfdylse E++++k+++HpN v+l++v+++++ y+++E++ G L dyl+ ah02979 323 --EAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYG----NLLDYLR- 365 trrkgpllfsedeakkialQilrgleYLHsngiiHRDLKPeNILldnngv ++ + ++ +a+Qi +++eYL ++++iHRDL N+L+ +n ah02979 366 ECNRQEV--NAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHL 413 vdaflKiaDFGlAkkls...t.sss.lttfvGTpwYmAPEvllggngygt v K+aDFGl++++ +++++ +++ + + + APE l +n+ + ah02979 414 V----KVADFGLSRLMTgdtYtAHAgAKFP---IKWTAPESLA-YNKFSI 455 kvDvWSlGvilyellt.GkpPFsgevqdsldqlqlirkilgpplefdspe k+DvW++Gv+l+e +t G P++g d q++++ + +++ ++pe ah02979 456 KSDVWAFGVLLWEIATyGMSPYPGI-----DLSQVYELLEK-DYRMERPE 499 wdsisrsefrrlpnlseeakdLikkcLnkDPskRltaeeilqHPwf<-* ++ e +L++ c++++Ps+R++++ei q f ah02979 500 GCP-------------EKVYELMRACWQWNPSDRPSFAEIHQA--F 530 PF08919.1.fs: domain 1 of 1, from 990 to 1167: score 476.2, E = 3.6e-140 *->EGlkKavlpavPksqkaakPvGtPpspvplPstsispsklangtqPS EGlkK+vlpa+Pk+q+ akP+GtP+sp+p+Pst++s+s++++g+qPS ah02979 990 EGLKKPVLPATPKPQS-AKPSGTPISPAPVPSTLPSASSALAGDQPS 1035 SaAFiPLisTrVsLRKTrQaaErIasdkItKevvLdstelLslAisRNSE S+AFiPLisTrVsLRKTrQ++ErIas++ItK+vvLdste+L+lAisRNSE ah02979 1036 STAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSE 1085 emvshSavleaGknLydfCvsYVDSIqQmRNKFAFREAinKLElnLrELQ +m+shSavleaGknLy+fCvsYVDSIqQmRNKFAFREAinKLE+nLrELQ ah02979 1086 QMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQ 1135 issatAgSgPaatqdlskLLSsVkEISDiVqR<-* i++atAgSgPaatqd+skLLSsVkEISDiVqR ah02979 1136 ICPATAGSGPAATQDFSKLLSSVKEISDIVQR 1167 PF08919.1.ls: domain 1 of 1, from 990 to 1167: score 478.2, E = 9.2e-141 *->EGlkKavlpavPksqkaakPvGtPpspvplPstsispsklangtqPS EGlkK+vlpa+Pk+q+ akP+GtP+sp+p+Pst++s+s++++g+qPS ah02979 990 EGLKKPVLPATPKPQS-AKPSGTPISPAPVPSTLPSASSALAGDQPS 1035 SaAFiPLisTrVsLRKTrQaaErIasdkItKevvLdstelLslAisRNSE S+AFiPLisTrVsLRKTrQ++ErIas++ItK+vvLdste+L+lAisRNSE ah02979 1036 STAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSE 1085 emvshSavleaGknLydfCvsYVDSIqQmRNKFAFREAinKLElnLrELQ +m+shSavleaGknLy+fCvsYVDSIqQmRNKFAFREAinKLE+nLrELQ ah02979 1086 QMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQ 1135 issatAgSgPaatqdlskLLSsVkEISDiVqR<-* i++atAgSgPaatqd+skLLSsVkEISDiVqR ah02979 1136 ICPATAGSGPAATQDFSKLLSSVKEISDIVQR 1167 //