hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080810/iprscan-20080810-02463220/chunk_1/iprscan-20080810-02463220.nocrc
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Query sequence: fh23263
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N 
--------  -----------                                   -----    ------- ---
PF00330.10.fs Aconitase family (aconitate hydratase)        479.3   4.3e-141   2
PF00330.10.ls Aconitase family (aconitate hydratase)        421.0   1.6e-123   1

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
PF00330.10.fs   1/2      90   161 ..     1    77 [.    57.1  1.4e-15
PF00330.10.ls   1/1      90   671 ..     1   512 []   421.0 1.6e-123
PF00330.10.fs   2/2     256   671 ..    99   512 .]   422.2 6.8e-124

Alignments of top-scoring domains:
PF00330.10.fs: domain 1 of 2, from 90 to 161: score 57.1, E = 1.4e-15
                   *->TlyeKildaHvvdpadqdiergtslLylRPdRvlmqdvTspqAflgL
                       +  +++  ++++      ++++ +  + P+Rvl qd+T+ +A++++
     fh23263    90    -MKKEDVMNILDWKT----KQSNVEVPFFPARVLLQDFTGIPAMVDF 131  

                   raagrpvrrvdgdadKvsPLSPttitcDHn<-*
                   +a++++v+ ++gd +Kv P  Pt++t+DH+   
     fh23263   132 AAMREAVKTLGGDPEKVHPACPTDLTVDHS    161  

PF00330.10.ls: domain 1 of 1, from 90 to 671: score 421.0, E = 1.6e-123
                   *->TlyeKildaHvvdpadqdiergtslLylRPdRvlmqdvTspqAflgL
                       +  +++  ++++      ++++ +  + P+Rvl qd+T+ +A++++
     fh23263    90    -MKKEDVMNILDWKT----KQSNVEVPFFPARVLLQDFTGIPAMVDF 131  

                   raagrpvrrvdgdadKvsPLSPttitcDHni...................
                   +a++++v+ ++gd +Kv P  Pt++t+DH+ + + ++   ++ +++++++
     fh23263   132 AAMREAVKTLGGDPEKVHPACPTDLTVDHSLqidfskcaiqnapnpgggd 181  

                   .....................ptqkggekkalE............vDlni
                    ++ ++ ++ + ++++ + +++t+ +g+ ++ E ++++++ +++ ++++i
     fh23263   182 lqkagklsplkvqpkklpcrgQTTCRGSCDSGElgrnsgtfssqiENTPI 231  

                   .....................eiernkeqydfLeknvkeFgvgfwgpgsk
                     + + ++ +++++  ++++ e  rn+e+ +f+++    F + ++ p+++
     fh23263   232 lcpfhlqpvpepetvlknqevEFGRNRERLQFFKWSSRVFKNVAVIPPGT 281  

                   rQGIvHqigLEnGftlPGlelqDGeliAYPDtlVGtDSHTpthGgLGaLA
                     G  Hqi+LE++   +       + + +PD +VGtDSH ++ +gLG L+
     fh23263   282 --GMAHQINLEYLSRVVFE----EKDLLFPDSVVGTDSHITMVNGLGILG 325  

                   fGvGgsEaEhVlAgqplelkkPKvmgikltGklngGitaKDvILkvigll
                   +GvGg+E E+V++g p++l  P+v+g +ltG+ n+ +t+ Dv+L ++  l
     fh23263   326 WGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHL 375  

                   tvkGGTGkvVEffGegiddLSmegRaTICNMaiEiGAtaGlfppDettfk
                   +  G+ Gk+VEffG+g++ LS  +R TI+NM +E+GA  ++fp+D +t+k
     fh23263   376 RQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLK 425  

                   YlkgrgrapkaeeadeavakwktL.ksDkdAneEPqyDkvveldlsdieP
                    l+ +g ++   e  e + k+ +L + D +   EP+y +v++++l++i P
     fh23263   426 HLEHTGFSKAKLESMETYLKAVKLfRNDQNSSGEPEYSQVIQINLNSIVP 475  

                   svtGPttPqdavpiselvpepkn..N.......vldpvkkakaerAlaYm
                   sv GP++Pqd+v+++++++++++  N++ + +++ + ++k+k+   ++Y 
     fh23263   476 SVSGPKRPQDRVAVTDMKSDFQAclNekvgfkgFQIAAEKQKDIVSIHYE 525  

                   glwpgtqlkeikVdvafIGSCTNssieDlrrAAsivkgaaaekGkklkpk
                   g +   +l+++ V++a+  SCTN  ++++  AA++++++a+e G+ +kp 
     fh23263   526 GSEY--KLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKPY 573  

                   vkatVvPGSeqVkataEreGLdkiFkeaGfewranGCspCiGmnd.rpDi
                   ++ ++ PGS+ V+ ++   G  +++  +Gfe +++GCs+C G+  ++ D 
     fh23263   574 IRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTApLSDA 623  

                   lkeavkkgDekercvsssNRNFeGRqgangrThafLaSPalvaAaAiaG<
                      avk+gD++   ++s+N NFeGR    +r++ +LaSP+lv+A+AiaG 
     fh23263   624 VLNAVKQGDLVTCGILSGNKNFEGRLCDCVRAN-YLASPPLVVAYAIAG  671  

                   -*
                     
     fh23263     -    -    

PF00330.10.fs: domain 2 of 2, from 256 to 671: score 422.2, E = 6.8e-124
                   *->rnkeqydfLeknvkeFgvgfwgpgskrQGIvHqigLEnGftlPGlel
                      rn+e+ +f+++    F + ++ p+++  G  Hqi+LE++   +    
     fh23263   256    RNRERLQFFKWSSRVFKNVAVIPPGT--GMAHQINLEYLSRVVFE-- 298  

                   qDGeliAYPDtlVGtDSHTpthGgLGaLAfGvGgsEaEhVlAgqplelkk
                      + + +PD +VGtDSH ++ +gLG L++GvGg+E E+V++g p++l  
     fh23263   299 --EKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTL 346  

                   PKvmgikltGklngGitaKDvILkviglltvkGGTGkvVEffGegiddLS
                   P+v+g +ltG+ n+ +t+ Dv+L ++  l+  G+ Gk+VEffG+g++ LS
     fh23263   347 PEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLS 396  

                   megRaTICNMaiEiGAtaGlfppDettfkYlkgrgrapkaeeadeavakw
                     +R TI+NM +E+GA  ++fp+D +t+k l+ +g ++   e  e + k+
     fh23263   397 IVDRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKA 446  

                   ktL.ksDkdAneEPqyDkvveldlsdiePsvtGPttPqdavpiselvpep
                    +L + D +   EP+y +v++++l++i Psv GP++Pqd+v+++++++++
     fh23263   447 VKLfRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDF 496  

                   kn..N.......vldpvkkakaerAlaYmglwpgtqlkeikVdvafIGSC
                   ++  N++ + +++ + ++k+k+   ++Y g +   +l+++ V++a+  SC
     fh23263   497 QAclNekvgfkgFQIAAEKQKDIVSIHYEGSEY--KLSHGSVVIAAVISC 544  

                   TNssieDlrrAAsivkgaaaekGkklkpkvkatVvPGSeqVkataEreGL
                   TN  ++++  AA++++++a+e G+ +kp ++ ++ PGS+ V+ ++   G 
     fh23263   545 TNNCNPSVMLAAGLLAKKAVEAGLRVKPYIRTSLSPGSGMVTHYLSSSGV 594  

                   dkiFkeaGfewranGCspCiGmnd.rpDilkeavkkgDekercvsssNRN
                    +++  +Gfe +++GCs+C G+  ++ D    avk+gD++   ++s+N N
     fh23263   595 LPYLSKLGFEIVGYGCSTCVGNTApLSDAVLNAVKQGDLVTCGILSGNKN 644  

                   FeGRqgangrThafLaSPalvaAaAiaG<-*
                   FeGR    +r++ +LaSP+lv+A+AiaG   
     fh23263   645 FEGRLCDCVRAN-YLASPPLVVAYAIAG    671  

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