hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080812/iprscan-20080812-04135397/chunk_1/iprscan-20080812-04135397.nocrc
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Query sequence: hg04377
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF00617.10.ls RasGEF domain                                  204.3    2.6e-58   1
PF00617.10.fs RasGEF domain                                  202.5    8.9e-58   1
PF00618.10.fs Guanine nucleotide exchange factor for Ras-l    80.4    7.3e-23   1
PF00618.10.ls Guanine nucleotide exchange factor for Ras-l    82.2    1.5e-21   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF00618.10.fs   1/1     908  1002 ..     1   109 []    80.4  7.3e-23
PF00618.10.ls   1/1     908  1002 ..     1   109 []    82.2  1.5e-21
PF00617.10.fs   1/1    1054  1231 ..     1   227 []   202.5  8.9e-58
PF00617.10.ls   1/1    1054  1231 ..     1   227 []   204.3  2.6e-58

Alignments of top-scoring domains:
PF00618.10.fs: domain 1 of 1, from 908 to 1002: score 80.4, E = 7.3e-23
                   *->qvkagtlekLvehLtshsklDss.FvstFLlTYRsFttpaeLlekLi
                       v++g+ + L++h+t  + +D   ++++FL+TYR+F++p+eL++kL+
     hg04377   908    DVRGGSGDILLVHATETDRKDLVlYCEAFLTTYRTFISPEELIKKLQ 954  

                   eRywseippp.nl.qssknsweekkkllkpiqlrvlnvlrhWvenyf.eD
                   +Ry  e + p +++              k++ ++++ vl + v++    +
     hg04377   955 YRY--EKFSPfADtFK------------KRVSKNTFFVLVRVVDELClVE 990  

                   FadeddpellsrLleF<-*
                   +    ++e l++L+e+   
     hg04377   991 L----TEEILKLLMEL    1002 

PF00618.10.ls: domain 1 of 1, from 908 to 1002: score 82.2, E = 1.5e-21
                   *->qvkagtlekLvehLtshsklDss.FvstFLlTYRsFttpaeLlekLi
                       v++g+ + L++h+t  + +D   ++++FL+TYR+F++p+eL++kL+
     hg04377   908    DVRGGSGDILLVHATETDRKDLVlYCEAFLTTYRTFISPEELIKKLQ 954  

                   eRywseippp.nl.qssknsweekkkllkpiqlrvlnvlrhWvenyf.eD
                   +Ry  e + p +++              k++ ++++ vl + v++    +
     hg04377   955 YRY--EKFSPfADtFK------------KRVSKNTFFVLVRVVDELClVE 990  

                   FadeddpellsrLleF<-*
                   +    ++e l++L+e+   
     hg04377   991 L----TEEILKLLMEL    1002 

PF00617.10.fs: domain 1 of 1, from 1054 to 1231: score 202.5, E = 8.9e-58
                   *->LlldplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                      +++++ e+A+QLTLl++elf+kI+++e L           W k+   
     hg04377  1054    HDFHSHEIAEQLTLLDAELFYKIEIPEVLL----------WAKE--- 1087 

                   vkneripnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                    ++e +pn+++++ +fN+ + +v + I +qe           ++ +R ++
     hg04377  1088 QNEEKSPNLTQFTEHFNNMSYWVRSIIMLQE-----------KAQDRERL 1126 

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   + kfI ++ h+R+LnNFnS laI+sAL s+pI RL++      +q+    
     hg04377  1127 LLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEW-----QKQTSEG- 1170 

                   feeLnkLmdsdrNfsnyRelLksigplappnLdddfvraPCVPFfGvYLs
                   + e  +L+ds+  f+ yR  L+ + p             PC+P++G++L 
     hg04377  1171 LAEYCTLIDSSSSFRAYRAALSEVEP-------------PCIPYLGLILQ 1207 

                   DLtfleeGnpdyleekKINtnlvNFsKrrk<-*
                   DLtf++ Gnpdy        ++vNFsKr +   
     hg04377  1208 DLTFVHLGNPDYID------GKVNFSKRWQ    1231 

PF00617.10.ls: domain 1 of 1, from 1054 to 1231: score 204.3, E = 2.6e-58
                   *->LlldplelAkQLTLlEhelfkkItpfefLgsKmKHEGPqvWgkksfk
                      +++++ e+A+QLTLl++elf+kI+++e L           W k+   
     hg04377  1054    HDFHSHEIAEQLTLLDAELFYKIEIPEVLL----------WAKE--- 1087 

                   vkneripnidktiknfNqltnfvsetIlkqeFPTNPEFSKkvdpkkRaev
                    ++e +pn+++++ +fN+ + +v + I +qe           ++ +R ++
     hg04377  1088 QNEEKSPNLTQFTEHFNNMSYWVRSIIMLQE-----------KAQDRERL 1126 

                   iqkfIqVAdhcReLnNFnSllaIisALysspIyRLkkTWekvppqslklI
                   + kfI ++ h+R+LnNFnS laI+sAL s+pI RL++      +q+    
     hg04377  1127 LLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEW-----QKQTSEG- 1170 

                   feeLnkLmdsdrNfsnyRelLksigplappnLdddfvraPCVPFfGvYLs
                   + e  +L+ds+  f+ yR  L+ + p             PC+P++G++L 
     hg04377  1171 LAEYCTLIDSSSSFRAYRAALSEVEP-------------PCIPYLGLILQ 1207 

                   DLtfleeGnpdyleekKINtnlvNFsKrrk<-*
                   DLtf++ Gnpdy        ++vNFsKr +   
     hg04377  1208 DLTFVHLGNPDYID------GKVNFSKRWQ    1231 

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