# /hgtech/tools/solaris8/bin/fasta34_t -T 8 -b50 -d10 -E0.01 -H -Ohj02541.fasta.nr -Q hj02541.ptfa /cdna2/lib/nr/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 hj02541, 1049 aa vs /cdna2/lib/nr/nr library 2362217958 residues in 6843189 sequences statistics sampled from 60000 to 6836763 sequences Expectation_n fit: rho(ln(x))= 5.7969+/-0.000192; mu= 11.7155+/- 0.011 mean_var=98.5390+/-18.956, 0's: 36 Z-trim: 57 B-trim: 116 in 1/65 Lambda= 0.129202 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 39, opt: 27, open/ext: -10/-2, width: 16 The best scores are: opt bits E(6843189) gi|168278108|dbj|BAG11032.1| FERM, RhoGEF and plec (1045) 6995 1315.1 0 gi|74762059|sp|Q9Y4F1|FARP1_HUMAN FERM, RhoGEF and (1045) 6988 1313.8 0 gi|114650398|ref|XP_001142564.1| PREDICTED: FERM, (1045) 6963 1309.1 0 gi|114650404|ref|XP_001142428.1| PREDICTED: FERM, (1045) 6934 1303.7 0 gi|75070718|sp|Q5RAB8.1|FARP1_PONAB FERM, RhoGEF a (1045) 6857 1289.3 0 gi|109121202|ref|XP_001089334.1| PREDICTED: simila (1078) 6656 1251.9 0 gi|149730458|ref|XP_001491048.1| PREDICTED: FERM, (1046) 6588 1239.2 0 gi|149050235|gb|EDM02559.1| FERM, RhoGEF (Arhgef) (1049) 6482 1219.4 0 gi|149266279|ref|XP_001473991.1| PREDICTED: simila (1048) 6477 1218.5 0 gi|162319134|gb|AAI56365.1| FERM, RhoGEF (Arhgef) (1048) 6472 1217.6 0 gi|148668275|gb|EDL00605.1| FERM, RhoGEF (Arhgef) (1047) 6443 1212.2 0 gi|119904908|ref|XP_610432.3| PREDICTED: similar t (1046) 6433 1210.3 0 gi|126337325|ref|XP_001366226.1| PREDICTED: simila (1045) 6272 1180.3 0 gi|126337327|ref|XP_001366274.1| PREDICTED: simila (1045) 6253 1176.8 0 gi|149411782|ref|XP_001506249.1| PREDICTED: simila (1047) 6175 1162.2 0 gi|73989436|ref|XP_534170.2| PREDICTED: similar to (1019) 6060 1140.8 0 gi|118084665|ref|XP_416976.2| PREDICTED: similar t (1019) 5893 1109.6 0 gi|47940452|gb|AAH71592.1| FARP1 protein [Homo sap (1076) 5073 956.8 0 gi|20987936|gb|AAH30329.1| Farp1 protein [Mus musc ( 835) 5071 956.4 0 gi|114650402|ref|XP_001142102.1| PREDICTED: FERM, (1022) 5060 954.4 0 gi|114650396|ref|XP_509707.2| PREDICTED: FERM, Rho (1076) 5060 954.4 0 gi|109101719|ref|XP_001091489.1| PREDICTED: simila (1055) 3796 718.8 3.2e-204 gi|194211521|ref|XP_001497741.2| PREDICTED: FERM, (1047) 3763 712.6 2.3e-202 gi|81916097|sp|Q91VS8|FARP2_MOUSE FERM, RhoGEF and (1065) 3747 709.6 1.8e-201 gi|74152708|dbj|BAE42626.1| unnamed protein produc (1065) 3737 707.8 6.6e-201 gi|73994333|ref|XP_543330.2| PREDICTED: similar to (1045) 3671 695.5 3.3e-197 gi|93204574|sp|O94887|FARP2_HUMAN FERM, RhoGEF and (1054) 3387 642.5 2.9e-181 gi|13278388|gb|AAH04009.1| Farp1 protein [Mus musc ( 420) 2701 514.3 4.5e-143 gi|194671909|ref|XP_001250662.2| PREDICTED: simila ( 411) 2613 497.9 3.8e-138 gi|47220960|emb|CAF98189.1| unnamed protein produc (1425) 2417 461.8 9.6e-127 gi|20071585|gb|AAH27077.1| Farp1 protein [Mus musc ( 354) 2273 434.5 4.1e-119 gi|149037487|gb|EDL91918.1| FERM, RhoGEF and pleck (1060) 2086 400.0 2.9e-108 gi|28175182|gb|AAH43327.1| Farp1 protein [Mus musc ( 307) 1963 376.7 9.1e-102 gi|18204275|gb|AAH21301.1| FARP2 protein [Homo sap ( 647) 1729 333.3 2.1e-88 gi|26330290|dbj|BAC28875.1| unnamed protein produc ( 268) 1720 331.3 3.5e-88 gi|189523215|ref|XP_001343862.2| PREDICTED: simila ( 758) 1721 331.9 6.8e-88 gi|189520239|ref|XP_001922651.1| PREDICTED: FERM, (1044) 1543 298.8 8.4e-78 gi|194040687|ref|XP_001926834.1| PREDICTED: simila ( 740) 1504 291.4 1e-75 gi|109132269|ref|XP_001095803.1| PREDICTED: simila ( 714) 1459 283.0 3.3e-73 gi|74749680|sp|Q6ZUT3|FRMD7_HUMAN FERM domain-cont ( 714) 1459 283.0 3.3e-73 gi|194228299|ref|XP_001915369.1| PREDICTED: FERM d ( 714) 1453 281.9 7.1e-73 gi|194680154|ref|XP_001787430.1| PREDICTED: simila ( 726) 1406 273.1 3.1e-70 gi|123296778|emb|CAM15767.1| FERM domain containin ( 703) 1393 270.7 1.6e-69 gi|83405603|gb|AAI10756.1| MGC131000 protein [Xeno ( 378) 1381 268.3 4.8e-69 gi|118089423|ref|XP_426268.2| PREDICTED: hypotheti ( 693) 1384 269.0 5.1e-69 gi|47227033|emb|CAG05925.1| unnamed protein produc (1326) 1375 267.6 2.7e-68 gi|189514447|ref|XP_686048.2| PREDICTED: similar t ( 723) 1365 265.5 6.2e-68 gi|74008966|ref|XP_549262.2| PREDICTED: similar to ( 787) 1353 263.3 3.1e-67 gi|193617667|ref|XP_001943157.1| PREDICTED: simila (2271) 1352 263.5 7.8e-67 gi|109511213|ref|XP_229144.4| PREDICTED: similar t ( 693) 1341 261.0 1.3e-66 >>gi|168278108|dbj|BAG11032.1| FERM, RhoGEF and pleckstr (1045 aa) initn: 6995 init1: 6995 opt: 6995 Z-score: 7044.3 bits: 1315.1 E(): 0 Smith-Waterman score: 6995; 100.000% identity (100.000% similar) in 1045 aa overlap (5-1049:1-1045) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK 360 370 380 390 400 410 430 440 450 460 470 480 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG 420 430 440 450 460 470 490 500 510 520 530 540 hj0254 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF 480 490 500 510 520 530 550 560 570 580 590 600 hj0254 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT 540 550 560 570 580 590 610 620 630 640 650 660 hj0254 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK 600 610 620 630 640 650 670 680 690 700 710 720 hj0254 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDCRAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDCRAA 660 670 680 690 700 710 730 740 750 760 770 780 hj0254 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ 720 730 740 750 760 770 790 800 810 820 830 840 hj0254 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIV 780 790 800 810 820 830 850 860 870 880 890 900 hj0254 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS 840 850 860 870 880 890 910 920 930 940 950 960 hj0254 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF 900 910 920 930 940 950 970 980 990 1000 1010 1020 hj0254 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|168 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYT 960 970 980 990 1000 1010 1030 1040 hj0254 FERWMEVIRSATSSASRPHVLSHKESLVY ::::::::::::::::::::::::::::: gi|168 FERWMEVIRSATSSASRPHVLSHKESLVY 1020 1030 1040 >>gi|74762059|sp|Q9Y4F1|FARP1_HUMAN FERM, RhoGEF and ple (1045 aa) initn: 6988 init1: 6988 opt: 6988 Z-score: 7037.2 bits: 1313.8 E(): 0 Smith-Waterman score: 6988; 99.904% identity (100.000% similar) in 1045 aa overlap (5-1049:1-1045) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK 360 370 380 390 400 410 430 440 450 460 470 480 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG 420 430 440 450 460 470 490 500 510 520 530 540 hj0254 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF 480 490 500 510 520 530 550 560 570 580 590 600 hj0254 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT 540 550 560 570 580 590 610 620 630 640 650 660 hj0254 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK 600 610 620 630 640 650 670 680 690 700 710 720 hj0254 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDCRAA ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: gi|747 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPSHADFRDCRAA 660 670 680 690 700 710 730 740 750 760 770 780 hj0254 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ 720 730 740 750 760 770 790 800 810 820 830 840 hj0254 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIV 780 790 800 810 820 830 850 860 870 880 890 900 hj0254 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS 840 850 860 870 880 890 910 920 930 940 950 960 hj0254 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF 900 910 920 930 940 950 970 980 990 1000 1010 1020 hj0254 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|747 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYT 960 970 980 990 1000 1010 1030 1040 hj0254 FERWMEVIRSATSSASRPHVLSHKESLVY ::::::::::::::::::::::::::::: gi|747 FERWMEVIRSATSSASRPHVLSHKESLVY 1020 1030 1040 >>gi|114650398|ref|XP_001142564.1| PREDICTED: FERM, RhoG (1045 aa) initn: 6963 init1: 6963 opt: 6963 Z-score: 7012.0 bits: 1309.1 E(): 0 Smith-Waterman score: 6963; 99.426% identity (99.904% similar) in 1045 aa overlap (5-1049:1-1045) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK ::::::::::::::::::::::::::::::::::::.:::::::::::::::::.::::: gi|114 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSASLTFGEGAESPGGQSCRQGKEPK 360 370 380 390 400 410 430 440 450 460 470 480 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG 420 430 440 450 460 470 490 500 510 520 530 540 hj0254 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF 480 490 500 510 520 530 550 560 570 580 590 600 hj0254 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: gi|114 PTDKAYFIAKEVSITERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT 540 550 560 570 580 590 610 620 630 640 650 660 hj0254 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK 600 610 620 630 640 650 670 680 690 700 710 720 hj0254 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDCRAA ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: gi|114 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPSHADFRDCRAA 660 670 680 690 700 710 730 740 750 760 770 780 hj0254 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ 720 730 740 750 760 770 790 800 810 820 830 840 hj0254 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIV :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|114 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEDSEDEWGVPHCLTLRGQRQSIIV 780 790 800 810 820 830 850 860 870 880 890 900 hj0254 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS 840 850 860 870 880 890 910 920 930 940 950 960 hj0254 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF 900 910 920 930 940 950 970 980 990 1000 1010 1020 hj0254 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYT :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: gi|114 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYFFRAESEYT 960 970 980 990 1000 1010 1030 1040 hj0254 FERWMEVIRSATSSASRPHVLSHKESLVY ::::::::::::::::::::::::::::: gi|114 FERWMEVIRSATSSASRPHVLSHKESLVY 1020 1030 1040 >>gi|114650404|ref|XP_001142428.1| PREDICTED: FERM, RhoG (1045 aa) initn: 6934 init1: 6934 opt: 6934 Z-score: 6982.8 bits: 1303.7 E(): 0 Smith-Waterman score: 6934; 99.043% identity (99.713% similar) in 1045 aa overlap (5-1049:1-1045) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM ::::::::::::::::::::::::::::::::::::::::::::::::: . .::::::: gi|114 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANVTCRDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK ::::::::::::::::::::::::::::::::::::.:::::::::::::::::.::::: gi|114 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSASLTFGEGAESPGGQSCRQGKEPK 360 370 380 390 400 410 430 440 450 460 470 480 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG 420 430 440 450 460 470 490 500 510 520 530 540 hj0254 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF 480 490 500 510 520 530 550 560 570 580 590 600 hj0254 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: gi|114 PTDKAYFIAKEVSITERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT 540 550 560 570 580 590 610 620 630 640 650 660 hj0254 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK 600 610 620 630 640 650 670 680 690 700 710 720 hj0254 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDCRAA ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: gi|114 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPSHADFRDCRAA 660 670 680 690 700 710 730 740 750 760 770 780 hj0254 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ 720 730 740 750 760 770 790 800 810 820 830 840 hj0254 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIV :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|114 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEDSEDEWGVPHCLTLRGQRQSIIV 780 790 800 810 820 830 850 860 870 880 890 900 hj0254 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS 840 850 860 870 880 890 910 920 930 940 950 960 hj0254 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF 900 910 920 930 940 950 970 980 990 1000 1010 1020 hj0254 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYT :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: gi|114 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYFFRAESEYT 960 970 980 990 1000 1010 1030 1040 hj0254 FERWMEVIRSATSSASRPHVLSHKESLVY ::::::::::::::::::::::::::::: gi|114 FERWMEVIRSATSSASRPHVLSHKESLVY 1020 1030 1040 >>gi|75070718|sp|Q5RAB8.1|FARP1_PONAB FERM, RhoGEF and p (1045 aa) initn: 6857 init1: 6857 opt: 6857 Z-score: 6905.2 bits: 1289.3 E(): 0 Smith-Waterman score: 6857; 97.990% identity (99.234% similar) in 1045 aa overlap (5-1049:1-1045) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|750 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::::::::::::::::::::: :::::::::::::::.::::::::::::::: gi|750 PQRAPGKVLLDAVCNHLNLVEGDYFGLECPDHKKITVWLDLLKPLVKQIRRPKHVVVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|750 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|750 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|750 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|750 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK ::::::::::::::::::::::::: ::::::::::.::::::::::::::::..::::: gi|750 KKVQFERKHSKIHSIRSLASQPTELYSEVLEQSQQSASLTFGEGAESPGGQSCQQGKEPK 360 370 380 390 400 410 430 440 450 460 470 480 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG :: :::::::::.::::::::::::::::::::::::::::::::::::::::::::::: gi|750 VSPGEPGSHPSPVPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG 420 430 440 450 460 470 490 500 510 520 530 540 hj0254 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|750 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF 480 490 500 510 520 530 550 560 570 580 590 600 hj0254 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: gi|750 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSAVSKEDAMPEALKSLIFPNFEPLHKFHT 540 550 560 570 580 590 610 620 630 640 650 660 hj0254 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: gi|750 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAVHLWKHSEALEALENGIK 600 610 620 630 640 650 670 680 690 700 710 720 hj0254 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDCRAA :::::::::::::::::::::::::::::::: :::.::::::::::::::::::::::: gi|750 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRHMHYKQVLERLCKHHPPSHADFRDCRAA 660 670 680 690 700 710 730 740 750 760 770 780 hj0254 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|750 LAGITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ 720 730 740 750 760 770 790 800 810 820 830 840 hj0254 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIV ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: gi|750 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIKESEDEWGVPHCLTLRGQRQSIIV 780 790 800 810 820 830 850 860 870 880 890 900 hj0254 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS ::::::::::::::::::::::::.:: :::::::::::::::::::::::::::::::: gi|750 AASSRSEMEKWVEDIQMAIDLAEKNSSLAPEFLASSPPDNKSPDEATAADQESEDDLSAS 840 850 860 870 880 890 910 920 930 940 950 960 hj0254 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: gi|750 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSVAVENQLSGNLLRKFKNSNGWQKLWVVF 900 910 920 930 940 950 970 980 990 1000 1010 1020 hj0254 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYT ::::::::::::::::::::::::::::::.:::::.::::::::::::::::::::::: gi|750 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPTESENIHKDYVFKLHFKSHVYYFRAESEYT 960 970 980 990 1000 1010 1030 1040 hj0254 FERWMEVIRSATSSASRPHVLSHKESLVY ::::::::::::::::: :: :::::::: gi|750 FERWMEVIRSATSSASRVHVSSHKESLVY 1020 1030 1040 >>gi|109121202|ref|XP_001089334.1| PREDICTED: similar to (1078 aa) initn: 3894 init1: 3894 opt: 6656 Z-score: 6702.6 bits: 1251.9 E(): 0 Smith-Waterman score: 6656; 96.146% identity (98.266% similar) in 1038 aa overlap (5-1042:1-1032) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: gi|109 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDSSAALLISHIVQSEIGDFDEALD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK ::::::::::::::.:::::::::::::: ::::::.:::::::::::.::::..::::. gi|109 KKVQFERKHSKIHSVRSLASQPTELNSEVPEQSQQSASLTFGEGAESPAGQSCQQGKEPR 360 370 380 390 400 410 430 440 450 460 470 480 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG .:.:::::: :::::::.::::::::::::::::.::::::::::::::::::: gi|109 GFPRGAASRPSPAPR-SPAGNKQVDGAASAPTEEEEEVVKERTQQSKPQPPQPSTGSLTG 420 430 440 450 460 470 490 500 510 520 530 540 hj0254 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF ::::::::::::::::::.:::::::::::::.::::::::::::::::::::::::::: gi|109 SPHLSELSVNSQGGVAPAHVTLSPNLSPDTKQTSPLISPLLNDQACPRTDDEDEGRRKRF 480 490 500 510 520 530 550 560 570 580 590 600 hj0254 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: gi|109 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPETLKSLIFPNFEPLHKFHT 540 550 560 570 580 590 610 620 630 640 650 660 hj0254 NFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK :::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 NFLKEVEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIK 600 610 620 630 640 650 670 680 690 700 710 720 hj0254 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDCRAA ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: gi|109 SSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPSHADFRDCRAA 660 670 680 690 700 710 730 740 750 760 770 780 hj0254 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 LAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQ 720 730 740 750 760 770 790 800 810 820 830 840 hj0254 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 RMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIV 780 790 800 810 820 830 850 860 870 880 890 900 hj0254 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 AASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSAS 840 850 860 870 880 890 910 920 930 940 950 960 hj0254 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|109 RTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVF 900 910 920 930 940 950 970 980 990 1000 1010 1020 hj0254 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYT ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: gi|109 TNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIHKDYVFKLHFKSHVYYFRAESEYT 960 970 980 990 1000 1010 1030 1040 hj0254 FERWMEVIRSATSSASRPHVLSHKESLVY ::: :.. : ..:. : gi|109 FER-----PSGSLSRQKPNCTSGFAVCGCSSTSHAAAARAVAEMLFQVKGPYEEGKLFRV 1020 1030 1040 1050 1060 1070 >>gi|149730458|ref|XP_001491048.1| PREDICTED: FERM, RhoG (1046 aa) initn: 6586 init1: 3841 opt: 6588 Z-score: 6634.3 bits: 1239.2 E(): 0 Smith-Waterman score: 6588; 93.499% identity (98.566% similar) in 1046 aa overlap (5-1049:1-1046) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV ::::::::::::::::::::::::::.::::::::::::.:::::::::::::::: gi|149 MGEIEQRPTPGSRLGAPENSGISTLEHGQKPPPTPSGKLMSIKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : gi|149 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEASD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM ::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::: gi|149 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSSYQDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: gi|149 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKAVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK :::::::::::::::::::.::.: :::: .:.:::.:::.::::::: ::::..::: . gi|149 KKVQFERKHSKIHSIRSLATQPAEPNSEVPKQAQQSASLTLGEGAESPDGQSCQQGKELN 360 370 380 390 400 410 430 440 450 460 470 480 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTG .:..: : : ::: ..::.:::.::::..: .:::::::::::::::::::::::::::: gi|149 ASSAERGPHQSPALQKSPVGNKKADGAVKAMAEEEEEVVKDRTQQSKPQPPQPSTGSLTG 420 430 440 450 460 470 490 500 510 520 530 540 hj0254 SPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRF ::::::::.:::::..::::..::::::::::::::.:::::.:::::::::.::::::: gi|149 SPHLSELSINSQGGAVPANVVFSPNLSPDTKQASPLVSPLLNEQACPRTDDEEEGRRKRF 480 490 500 510 520 530 550 560 570 580 590 600 hj0254 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHT :::::::::::::::::::::::::::::::::::::..:::.::::::::::::::::: gi|149 PTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEESMPETLKSLIFPNFEPLHKFHT 540 550 560 570 580 590 610 620 630 640 650 hj0254 NFLKEIEQRLALWEGRSNAQIR-DYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGI :::::::::::::::::::.:: :.:::::::::::::::.::::::::.:::::::.:: gi|149 NFLKEIEQRLALWEGRSNAHIRGDHQRIGDVMLKNIQGMKQLAAHLWKHGEALEALETGI 600 610 620 630 640 650 660 670 680 690 700 710 hj0254 KSSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDCRA .:::::::.::::::::::::::::::::::::::::.:::::::::::::: ::::::: gi|149 RSSRRLENLCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPSHMDFRDCRA 660 670 680 690 700 710 720 730 740 750 760 770 hj0254 ALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQ :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: gi|149 ALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVIPGREFIRLGSLSKLSGKGLQ 720 730 740 750 760 770 780 790 800 810 820 830 hj0254 QRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSII :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 QRMFFLFNDILLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSII 780 790 800 810 820 830 840 850 860 870 880 890 hj0254 VAASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSA :::::::::::::::::::::::::::.:.::::::::::::::::...::::::::::: gi|149 VAASSRSEMEKWVEDIQMAIDLAEKSSGPTPEFLASSPPDNKSPDETAVADQESEDDLSA 840 850 860 870 880 890 900 910 920 930 940 950 hj0254 SRTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVV :::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: gi|149 SRTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSVAVENQLSGNLLRKFKNSNGWQKLWVV 900 910 920 930 940 950 960 970 980 990 1000 1010 hj0254 FTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEY :::::::::::::::::::::::::::::::::::...:::::::::::::::::::::: gi|149 FTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESEDVHKDYVFKLHFKSHVYYFRAESEY 960 970 980 990 1000 1010 1020 1030 1040 hj0254 TFERWMEVIRSATSSASRPHVLSHKESLVY :::::::::::::::::: :.:::::: :: gi|149 TFERWMEVIRSATSSASRAHILSHKESHVY 1020 1030 1040 >>gi|149050235|gb|EDM02559.1| FERM, RhoGEF (Arhgef) and (1049 aa) initn: 5501 init1: 2763 opt: 6482 Z-score: 6527.5 bits: 1219.4 E(): 0 Smith-Waterman score: 6482; 92.088% identity (97.521% similar) in 1049 aa overlap (5-1049:1-1049) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV ::::::.:::.::::::::::::::::::::::::::::...:::::::::::::: gi|149 MGEIEQKPTPASRLGAPENSGISTLERGQKPPPTPSGKLMTVKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::.::::::::::::::::::::::.::.:::::::::::::::::::.:::: gi|149 PQRAPGKVLFDAVCNHLNLVEGDYFGLEFPDHRKIVVWLDLLKPIVKQIRRPKHVLVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::.:::::::::::::::.:::::::::::::::.:::::::::::::::::: gi|149 REHLAKNKYVPQQDALEDKIVEFHHSHIGQTPAESDFQLLEVARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM :::::::::::::::::::::::::::::::::::::::::::::::.::.::::::::: gi|149 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 AGRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK :::::::::::::: :::.:::: :::: .:: ::.:::::::.:::..:::...:: : gi|149 KKVQFERKHSKIHSTRSLVSQPTAPNSEVPKQSPQSASLTFGEGTESPSAQSCQQAKETK 360 370 380 390 400 410 430 440 450 460 470 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADG-AASAPTEEE--EEVVKDRTQQSKPQPPQPSTGS : . ::: . ::: .::.:.: ::: ::.:: ::: :: :: . :.:::::::::: gi|149 VCTLEPGPRQSPALSKSPSGSKAADGTAAAAPPEEEDEEEGGKDGIRPSNPQPPQPSTGS 420 430 440 450 460 470 480 490 500 510 520 530 hj0254 LTGSPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRR :::::::::::.:::::.::::::::::::::.::::::::::::::::::::::.:::: gi|149 LTGSPHLSELSINSQGGAAPANVTLSPNLSPDNKQASPLISPLLNDQACPRTDDEEEGRR 480 490 500 510 520 530 540 550 560 570 580 590 hj0254 KRFPTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHK :::::::::.:::::::::::::::::::.:::::::::::.:::::::::::::::::: gi|149 KRFPTDKAYYIAKEVSTTERTYLKDLEVIASWFQSTVSKEDSMPEALKSLIFPNFEPLHK 540 550 560 570 580 590 600 610 620 630 640 650 hj0254 FHTNFLKEIEQRLALWEGRSNAQIR-DYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALE ::::::::::::::::::::::.:: :::::::::::::::::::::::::::::::::: gi|149 FHTNFLKEIEQRLALWEGRSNAHIRGDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALE 600 610 620 630 640 650 660 670 680 690 700 710 hj0254 NGIKSSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRD ..::.:::::.:::::::::::::::::::::::::::::.::::::::::::.:::::: gi|149 TSIKGSRRLEHFCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPNHADFRD 660 670 680 690 700 710 720 730 740 750 760 770 hj0254 CRAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGK ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: gi|149 CRAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVIPGREFIRLGSLSKLSGK 720 730 740 750 760 770 780 790 800 810 820 830 hj0254 GLQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQ ::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::: gi|149 GLQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEEEWGVPHCLTLRGQRQ 780 790 800 810 820 830 840 850 860 870 880 890 hj0254 SIIVAASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDD :::::::::::::::.:::::::::::::..:.::.:::::::::::::::::::::::: gi|149 SIIVAASSRSEMEKWLEDIQMAIDLAEKSNGPTPELLASSPPDNKSPDEATAADQESEDD 840 850 860 870 880 890 900 910 920 930 940 950 hj0254 LSASRTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKL ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::: gi|149 LSASRTSLERQAPHRGNTMVHVCWHRSTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKL 900 910 920 930 940 950 960 970 980 990 1000 1010 hj0254 WVVFTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAE :::::::::::::::::.::::::::::::::::::::::.::::::::::::::::::: gi|149 WVVFTNFCLFFYKSHQDSHPLASLPLLGYSLTIPSESENIHKDYVFKLHFKSHVYYFRAE 960 970 980 990 1000 1010 1020 1030 1040 hj0254 SEYTFERWMEVIRSATSSASRPHVLSHKESLVY ::::::::::::::::::::: : :::::: .: gi|149 SEYTFERWMEVIRSATSSASRAHSLSHKESHLY 1020 1030 1040 >>gi|149266279|ref|XP_001473991.1| PREDICTED: similar to (1048 aa) initn: 5489 init1: 2752 opt: 6477 Z-score: 6522.4 bits: 1218.5 E(): 0 Smith-Waterman score: 6477; 91.698% identity (97.424% similar) in 1048 aa overlap (5-1049:1-1048) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV ::::::.:::.::::::::::::::::::::::::::::...:::::::::::::: gi|149 MGEIEQKPTPASRLGAPENSGISTLERGQKPPPTPSGKLMTVKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::.::::::::::::::::::::::.::.:::::::::::::::::::::::: gi|149 PQRAPGKVLFDAVCNHLNLVEGDYFGLEFPDHRKIVVWLDLLKPIVKQIRRPKHVVVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::.::::::::.:.::::.:.:::::::::::::.:::::::::::::::::: gi|149 REHLAKNKYVPQQDALEDRIMEFHHSHVGQTPAESDFQLLEVARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM :::::::::::::::::::::::::::::::::::::::::::::::.::.::::::::: gi|149 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|149 AGRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK :::::::::::::: :::.:::: :::: .:: ::.:::::::.::::::::...:: : gi|149 KKVQFERKHSKIHSTRSLVSQPTAPNSEVPKQSPQSASLTFGEGTESPGGQSCQQAKETK 360 370 380 390 400 410 430 440 450 460 470 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVV--KDRTQQSKPQPPQPSTGSL . . : : : ::: .:: :.: :::.. .: ::::: :: . :.::::::::::: gi|149 ACTLELGPHQSPALPKSPPGSKAADGTTVVPPEEEEEEEGGKDGIRPSNPQPPQPSTGSL 420 430 440 450 460 470 480 490 500 510 520 530 hj0254 TGSPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRK ::::::::::.:::::.::::::::::::::.::::::::::::::::::::::.::::: gi|149 TGSPHLSELSINSQGGAAPANVTLSPNLSPDNKQASPLISPLLNDQACPRTDDEEEGRRK 480 490 500 510 520 530 540 550 560 570 580 590 hj0254 RFPTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKF ::::::::.:::::::::::::::::::.:::::::::::.::::::::::::::::::: gi|149 RFPTDKAYYIAKEVSTTERTYLKDLEVIASWFQSTVSKEDSMPEALKSLIFPNFEPLHKF 540 550 560 570 580 590 600 610 620 630 640 650 hj0254 HTNFLKEIEQRLALWEGRSNAQIR-DYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALEN :::::::::::::::::::::.:: ::::::::::::::::::::::::::::::::::. gi|149 HTNFLKEIEQRLALWEGRSNAHIRGDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALET 600 610 620 630 640 650 660 670 680 690 700 710 hj0254 GIKSSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDC .::.:::::.:::::::::::::::::::::::::::::..:::::::::::.::::::: gi|149 SIKGSRRLEHFCRDFELQKVCYLPLNTFLLRPLHRLMHYKHVLERLCKHHPPNHADFRDC 660 670 680 690 700 710 720 730 740 750 760 770 hj0254 RAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKG :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: gi|149 RAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVIPGREFIRLGSLSKLSGKG 720 730 740 750 760 770 780 790 800 810 820 830 hj0254 LQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQS :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: gi|149 LQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEEEWGVPHCLTLRGQRQS 780 790 800 810 820 830 840 850 860 870 880 890 hj0254 IIVAASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDL ::::::::::::::.:::::::::::::..:.::.::::::::::::::::::::::::: gi|149 IIVAASSRSEMEKWMEDIQMAIDLAEKSNGPTPELLASSPPDNKSPDEATAADQESEDDL 840 850 860 870 880 890 900 910 920 930 940 950 hj0254 SASRTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLW :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: gi|149 SASRTSLERQAPHRGNTMVHVCWHRSTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLW 900 910 920 930 940 950 960 970 980 990 1000 1010 hj0254 VVFTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAES ::::::::::::::::.::::::::::::::::::::::.:::::::::::::::::::: gi|149 VVFTNFCLFFYKSHQDSHPLASLPLLGYSLTIPSESENIHKDYVFKLHFKSHVYYFRAES 960 970 980 990 1000 1010 1020 1030 1040 hj0254 EYTFERWMEVIRSATSSASRPHVLSHKESLVY :::::::::::::::::::: :.:::::: .: gi|149 EYTFERWMEVIRSATSSASRAHILSHKESHLY 1020 1030 1040 >>gi|162319134|gb|AAI56365.1| FERM, RhoGEF (Arhgef) and (1048 aa) initn: 6502 init1: 2751 opt: 6472 Z-score: 6517.4 bits: 1217.6 E(): 0 Smith-Waterman score: 6472; 91.603% identity (97.424% similar) in 1048 aa overlap (5-1049:1-1048) 10 20 30 40 50 60 hj0254 AAFIMGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEV ::::::.:::.::::::::::::::::::::::::::::...:::::::::::::: gi|162 MGEIEQKPTPASRLGAPENSGISTLERGQKPPPTPSGKLMTVKIQMLDDTQEAFEV 10 20 30 40 50 70 80 90 100 110 120 hj0254 PQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFV :::::::::.::::::::::::::::::::::.::.:::::::::::::::::::::::: gi|162 PQRAPGKVLFDAVCNHLNLVEGDYFGLEFPDHRKIVVWLDLLKPIVKQIRRPKHVVVKFV 60 70 80 90 100 110 130 140 150 160 170 180 hj0254 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|162 VKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALD 120 130 140 150 160 170 190 200 210 220 230 240 hj0254 REHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDRE :::::::::.::::::::.:.::::.:.:::::::::::::.:::::::::::::::::: gi|162 REHLAKNKYVPQQDALEDRIMEFHHSHVGQTPAESDFQLLEVARRLEMYGIRLHPAKDRE 180 190 200 210 220 230 250 260 270 280 290 300 hj0254 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLM :::::::::::::::::::::::::::::::::::::::::::::::.::.::::::::: gi|162 GTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLM 240 250 260 270 280 290 310 320 330 340 350 360 hj0254 ASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH :.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|162 AGRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGH 300 310 320 330 340 350 370 380 390 400 410 420 hj0254 KKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPK :::::::::::::: :::.:::: :::: .:: ::.:::::::.::::::::...:: : gi|162 KKVQFERKHSKIHSTRSLVSQPTAPNSEVPKQSPQSASLTFGEGTESPGGQSCQQAKETK 360 370 380 390 400 410 430 440 450 460 470 hj0254 VSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVV--KDRTQQSKPQPPQPSTGSL . . : : : ::: .:: :.: :::.. .: ::::: :: . :.::::::::::: gi|162 ACTLELGPHQSPALPKSPPGSKAADGTTVVPPEEEEEEEGGKDGIRPSNPQPPQPSTGSL 420 430 440 450 460 470 480 490 500 510 520 530 hj0254 TGSPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRK ::::::::::.:::::.::::::::::::::.::::::::::::::::::::::.::::: gi|162 TGSPHLSELSINSQGGAAPANVTLSPNLSPDNKQASPLISPLLNDQACPRTDDEEEGRRK 480 490 500 510 520 530 540 550 560 570 580 590 hj0254 RFPTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKF ::::::::.:::::::::::::::::::.:::::::::::.::::::::::::::::::: gi|162 RFPTDKAYYIAKEVSTTERTYLKDLEVIASWFQSTVSKEDSMPEALKSLIFPNFEPLHKF 540 550 560 570 580 590 600 610 620 630 640 650 hj0254 HTNFLKEIEQRLALWEGRSNAQIR-DYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALEN :::::::::::::::::::::..: ::::::::::::::::::::::::::::::::::. gi|162 HTNFLKEIEQRLALWEGRSNAHVRGDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALET 600 610 620 630 640 650 660 670 680 690 700 710 hj0254 GIKSSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYNQVLERLCKHHPPSHADFRDC .::.:::::.:::::::::::::::::::::::::::::..:::::::::::.::::::: gi|162 SIKGSRRLEHFCRDFELQKVCYLPLNTFLLRPLHRLMHYKHVLERLCKHHPPNHADFRDC 660 670 680 690 700 710 720 730 740 750 760 770 hj0254 RAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKG :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: gi|162 RAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVTPGREFIRLGSLSKLSGKG 720 730 740 750 760 770 780 790 800 810 820 830 hj0254 LQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQS :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: gi|162 LQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEEEWGVPHCLTLRGQRQS 780 790 800 810 820 830 840 850 860 870 880 890 hj0254 IIVAASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDL ::::::::::::::.:::::::::::::..:.::.::::::::::::::::::::::::: gi|162 IIVAASSRSEMEKWMEDIQMAIDLAEKSNGPTPELLASSPPDNKSPDEATAADQESEDDL 840 850 860 870 880 890 900 910 920 930 940 950 hj0254 SASRTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLW :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: gi|162 SASRTSLERQAPHRGNTMVHVCWHRSTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLW 900 910 920 930 940 950 960 970 980 990 1000 1010 hj0254 VVFTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAES ::::::::::::::::.::::::::::::::::::::::.:::::::::::::::::::: gi|162 VVFTNFCLFFYKSHQDSHPLASLPLLGYSLTIPSESENIHKDYVFKLHFKSHVYYFRAES 960 970 980 990 1000 1010 1020 1030 1040 hj0254 EYTFERWMEVIRSATSSASRPHVLSHKESLVY :::::::::::::::::::: :.:::::: .: gi|162 EYTFERWMEVIRSATSSASRAHILSHKESHLY 1020 1030 1040 1049 residues in 1 query sequences 2362217958 residues in 6843189 library sequences Tcomplib [34.26] (8 proc) start: Tue Aug 12 15:07:41 2008 done: Tue Aug 12 15:09:49 2008 Total Scan time: 1096.950 Total Display time: 0.700 Function used was FASTA [version 34.26.5 April 26, 2007]