hmmpfam - search one or more sequences against HMM database
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                 /db/iprscan/data/Pfam.bin
Sequence file:            /db/iprscan/tmp/20080813/iprscan-20080813-03294879/chunk_1/iprscan-20080813-03294879.nocrc
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Query sequence: hm00182
Accession:      [none]
Description:    [none]

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PF00621.11.fs RhoGEF domain                                   92.0    5.4e-27   1
PF00621.11.ls RhoGEF domain                                   93.8    4.7e-25   1
PF00169.19.fs PH domain                                       26.1    1.7e-07   1
PF00169.19.ls PH domain                                       25.5    0.00017   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PF00621.11.fs   1/1     137   314 ..     1   207 []    92.0  5.4e-27
PF00621.11.ls   1/1     137   314 ..     1   207 []    93.8  4.7e-25
PF00169.19.ls   1/1     323   460 ..     1    92 []    25.5  0.00017
PF00169.19.fs   1/1     353   460 ..    12    92 .]    26.1  1.7e-07

Alignments of top-scoring domains:
PF00621.11.fs: domain 1 of 1, from 137 to 314: score 92.0, E = 5.4e-27
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF
                      +++El + E+  ++dL +  + y  p+++ +     + t ++++ iF
     hm00182   137    AIFELSQGEEDLIEDLKLAKKAYHDPMLKLS-----IMTEQELNQIF 178  

                   sNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFlelk
                   + + +++ +h e+L+  L ++                s++ +G+++    
     hm00182   179 GTLDSLIPLHEELLS-QLRDVRKPD-----------GSTEHVGPILVGW- 215  

                   aeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd
                   ++ l+ Y +Ycsn+ +A+ ll++   +++ + ++ fl+++  s+      
     hm00182   216 LPCLSSYDSYCSNQVAAKALLDH---KKQDHRVQDFLQRCLESPFSR--- 259  

                   davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkkalda
                      kl+L  +L  P +R+ +YpLLL+e+L htp   d ++ + L++a+ +
     hm00182   260 ---KLDLWNFLDIPRSRLVKYPLLLREILRHTPN--DNPDQQHLEEAINI 304  

                   lqdlaksiNe<-*
                   +q++   iN    
     hm00182   305 IQGIVAEINT    314  

PF00621.11.ls: domain 1 of 1, from 137 to 314: score 93.8, E = 4.7e-25
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskplLtpddietiF
                      +++El + E+  ++dL +  + y  p+++ +     + t ++++ iF
     hm00182   137    AIFELSQGEEDLIEDLKLAKKAYHDPMLKLS-----IMTEQELNQIF 178  

                   sNiediyefhreFLkssLearisssnfedlDekkiepsaqrlGdlFlelk
                   + + +++ +h e+L+  L ++                s++ +G+++    
     hm00182   179 GTLDSLIPLHEELLS-QLRDVRKPD-----------GSTEHVGPILVGW- 215  

                   aeflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd
                   ++ l+ Y +Ycsn+ +A+ ll++   +++ + ++ fl+++  s+      
     hm00182   216 LPCLSSYDSYCSNQVAAKALLDH---KKQDHRVQDFLQRCLESPFSR--- 259  

                   davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedssesedLkkalda
                      kl+L  +L  P +R+ +YpLLL+e+L htp   d ++ + L++a+ +
     hm00182   260 ---KLDLWNFLDIPRSRLVKYPLLLREILRHTPN--DNPDQQHLEEAINI 304  

                   lqdlaksiNe<-*
                   +q++   iN    
     hm00182   305 IQGIVAEINT    314  

PF00169.19.ls: domain 1 of 1, from 323 to 460: score 25.5, E = 0.00017
                   *->vikeGwLlkkg...................gkkswkkRyfvLfddvL
                       +ke  L++ ++++++  ++++    +++ ++ +  k +++Lf+ vL
     hm00182   323    YYKERLLYLEEgqkdslidssrvvcchgelKNNRGVKLHVFLFQEVL 369  

                   lyykdkk.......kkpkgsipLsgiqvtkvpdn................
                   ++ +  +++++     ++  ip++++ ++++ d++ + +++ ++  ++++
     hm00182   370 VITRAVThneqlcyQLYRQPIPVKDLLLEDLQDGevrlggslrgafsnne 419  

                   krkncFeirt.dr...etlllqaeseeerkeWvkaiqsair<-*
                   + kn F+++++++++++t+ lqa++   +++W+++i++a     
     hm00182   420 RIKNFFRVSFkNGsqsQTHSLQANDTFNKQQWLNCIRQAKE    460  

PF00169.19.fs: domain 1 of 1, from 353 to 460: score 26.1, E = 1.7e-07
                   *->gkkswkkRyfvLfddvLlyykdkk.......kkpkgsipLsgiqvtk
                      ++ +  k +++Lf+ vL++ +  +++++     ++  ip++++ +++
     hm00182   353    KNNRGVKLHVFLFQEVLVITRAVThneqlcyQLYRQPIPVKDLLLED 399  

                   vpdn................krkncFeirt.dr...etlllqaeseeerk
                   + d++ + +++ ++  +++++ kn F+++++++++++t+ lqa++   ++
     hm00182   400 LQDGevrlggslrgafsnneRIKNFFRVSFkNGsqsQTHSLQANDTFNKQ 449  

                   eWvkaiqsair<-*
                   +W+++i++a     
     hm00182   450 QWLNCIRQAKE    460  

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