ORK04700

Kazusa Clone (Original Type)

Gene/Protein Characteristic Table for ORK04700

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Accession No	AB209492
Product ID	ORK04700
Clone name	ff04460
Vector information	The cDNA fragment was inserted at the SalI-NotI site of the ... The cDNA fragment was inserted at the SalI-NotI site of the pBluescript II SK(+) vector (GenBank Accession No. X52328). The 5' end of the cDNA was repaired and ligated with the SalI adapter (5'TCGACCCACGCGTCCG3') and inserted at the SalI site of the vector. The 3'end of the cDNA was inserted at the NotI site of the vector.
Symbol	CYP2D6
cDNA sequence	DNA sequence (3834 bp) Predicted protein sequence (467 aa)
Description	Cytochrome P450 2D6 (EC 1.14.14.1) (CYPIID6) (P450-DB1) (Debrisoquine 4-hydroxylase).

Features of the cloned cDNA sequence

Description

Length: 3834 bp

Physical map

Restriction map

Prediction of protein coding region (GeneMark analysis) for : cloned DNA seq.

Warning for N-terminal truncation: NO

Warning for coding interruption : YES

Features of the protein sequence

Description

Length: 467 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
AAA35737	2.5e-141	100.0	debrisoquine 4-...	Homo sapiens
AAA36403	1.3e-120	100.0	cytochrome P450...	Homo sapiens
ABB01371	1.6e-120	100.0	cytochrome P450...	Homo sapiens
EAW60493	2.2e-120	99.6	cytochrome P450...	Homo sapiens
ABB77902	2.4e-120	99.6	cytochrome P450...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR008069	147	159	PR01686	Cytochrome P450
	IPR002401	151	169	PR00463	Cytochrome P450
	IPR008069	193	206	PR01686	Cytochrome P450
	IPR008069	258	269	PR01686	Cytochrome P450
	IPR002401	264	281	PR00463	Cytochrome P450
	IPR001128	275	292	PR00385	Cytochrome P450
	IPR002401	284	310	PR00463	Cytochrome P450
	IPR002401	327	345	PR00463	Cytochrome P450
	IPR001128	328	339	PR00385	Cytochrome P450
	IPR002401	368	392	PR00463	Cytochrome P450
	IPR008069	368	382	PR01686	Cytochrome P450
	IPR002401	403	413	PR00463	Cytochrome P450
	IPR001128	404	413	PR00385	Cytochrome P450
	IPR001128	413	424	PR00385	Cytochrome P450
	IPR002401	413	436	PR00463	Cytochrome P450
HMMPfam	IPR001128	133	464	PF00067	Cytochrome P450
ScanRegExp	IPR001128	406	415	PS00086	Cytochrome P450

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