Kazusa Clone (Original Type)
Gene/Protein Characteristic Table for ORK04263
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Accession No AB209451
Product ID ORK04263
Clone name ah02705
Vector information
The cDNA fragment was inserted at the SalI-NotI site of the ...
Symbol BEST1
cDNA sequence DNA sequence (5762 bp)
Predicted protein sequence (376 aa)
Description Bestrophin-1 (Vitelliform macular dystrophy protein 2) (TU15B).
Features of the cloned cDNA sequence

Length: 5762 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for : cloned DNA seq.
Warning for N-terminal truncation: NO
Warning for coding interruption : YES
Integrity of 3' end
Length of 3'UTR 4256 bp
Genome contig ID gi51511727f_61374408
PolyA signal sequence
(GATAAA,-29)
+----*----+----*----+----*----+----
TTAATAGATAAAAATCCCAGACTACTTCAGCCTTT
Flanking genome sequence
(113936 - 113985)
----+----*----+----*----+----*----+----*----+----*
AATGCCTTTTATTCATAAAAACTGTGAAAGCTAGACTGAACCATTGGAAA

Features of the protein sequence

Length: 376 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
BAD92688 2.8e-156 100.0 bestrophin vari...
Homo sapiens
EAW73982 3.6e-110 97.8 vitelliform mac...
Homo sapiens
AAC64344 2.7e-109 97.5 bestrophin [Hom...
Homo sapiens
AAH15220 8.5e-81 96.7 BEST1 protein [...
Homo sapiens
XP_001116563 8.5e-81 96.7 similar to best...
Macaca mulatta
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
BlastProDom IPR000615 102 206 PD002802 Bestrophin
IPR000615 288 310 PD002802 Bestrophin
HMMPfam IPR000615 76 374 PF01062 Bestrophin

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 252 PLVYTQVVTVAVYSFFLTCLVGR 274 PRIMARY 23
2 291 VVPVFTFLQFFFYVGWLKVGLSR 313 SECONDARY 23
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