Kazusa Clone (Original Type)
Gene/Protein Characteristic Table for ORK06739
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Accession No AB208866
Product ID ORK06739
Clone name hg02374
Vector information
The cDNA fragment was inserted at the SalI-NotI site of the ...
Symbol SCN5A
cDNA sequence DNA sequence (7021 bp)
Predicted protein sequence (1576 aa)
Description Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).
Features of the cloned cDNA sequence

Length: 7021 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for : cloned DNA seq.
Warning for N-terminal truncation: YES
Warning for coding interruption : NO
Integrity of 3' end
Length of 3'UTR 2289 bp
Genome contig ID gi89161205r_38464552
PolyA signal sequence
(AATAAA,-23)
+----*----+----*----+----*----+----
TTAAAACAAACCAATAAATGGCTTACATGACCTGG
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
TCTAGGCTCTGTCCTTGTGCTGAGATTTGACAAGAGTGGTAGCAGAGGAC

Features of the protein sequence

Length: 1576 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
BAD92103 0 100.0 voltage-gated s...
Homo sapiens
NP_001092875 0 99.8 sodium channel ...
Homo sapiens
ABR15764 0 99.3 Nav1.5 Na+ chan...
Homo sapiens
XP_001917236 0 93.0 voltage-gated s...
Equus caballus
AAN61120 0 98.8 cardiac sodium ...
Homo sapiens
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR008053 23 37 PR01666 Na+ channel 5
IPR008053 84 104 PR01666 Na+ channel 5
IPR008053 206 223 PR01666 Na+ channel 5
IPR008053 553 571 PR01666 Na+ channel 5
IPR008053 602 618 PR01666 Na+ channel 5
IPR001696 1314 1333 PR00170 Na+ channel
IPR001696 1349 1362 PR00170 Na+ channel
HMMPfam IPR005821 330 517 PF00520 Ion transport
IPR010526 530 793 PF06512 Sodium ion transport-associated
IPR005821 819 1029 PF00520 Ion transport
IPR005821 1122 1331 PF00520 Ion transport
IPR000048 1462 1482 PF00612 IQ calmodulin-binding region

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 298 TDLTITMCIVLNTLFMALEHYN 319 SECONDARY 22
2 359 GWNIFDSIIVILSLMELGLSRMS 381 SECONDARY 23
3 387 RSFRLLRVFKLAKSWPTLNTLIK 409 SECONDARY 23
4 411 IGNSVGALGNLTLVLAIIVFIFA 433 PRIMARY 23
5 460 MMDFFHAFLIIFRILCGEWIETM 482 PRIMARY 23
6 498 FLLVMVIGNLVVLNLFLALLLSS 520 PRIMARY 23
7 785 FETFIIFMILLSSGALAFEDIYL 807 PRIMARY 23
8 817 LEYADKMFTYVFVLEMLLKWVAY 839 SECONDARY 23
9 847 NAWCWLDFLIVDVSLVSLVANTL 869 PRIMARY 23
10 906 VGAIPSIMNVLLVCLIFWLIFSI 928 PRIMARY 23
11 1008 IYFVIFIIFGSFFTLNLFIGVII 1030 PRIMARY 23
12 1089 AFDVTIMFLICLNMVTMMVETDD 1111 SECONDARY 23
13 1119 ILAKINLLFVAIFTGECIVKLAA 1141 SECONDARY 23
14 1150 SWNIFDFVVVILSIVGTVLSDII 1172 PRIMARY 23
15 1183 RVIRLARIGRILRLIRGAKGIRT 1205 SECONDARY 23
16 1210 LMMSLPALFNIGLLLFLVMFIYS 1232 PRIMARY 23
17 1251 MFNFQTFANSMLCLFQITTSAGW 1273 SECONDARY 23
18 1309 ILFFTTYIIISFLIVVNMYIAII 1331 PRIMARY 23
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