ORK01459

Kazusa Clone (Original Type)

Gene/Protein Characteristic Table for ORK01459

Order Kazusa clone(s) from :

Accession No
Product ID	ORK01459
Clone name	bm04933
Vector information	The cDNA fragment was inserted at the XhoI-SacI site of the ... The cDNA fragment was inserted at the XhoI-SacI site of the pBC SK+ vector (Cm resistance; http://www.kazusa.or.jp/huge/vectorinfo/pbcskp_s.txt) with sequences including attB1 and attB2 sites (CTCGAGCAGCTGAAGCTTTCACAAGTTTGTAC AAAAAAGCAGGCTCTTC-5' end of cDNA, GAGCTCTCACCACTTTGTAC AAGAAAGCTGGGCGGCCGCTTTTTTTTTTTTTTTTTT-3' end of cDNA).
Symbol	ABCG2
cDNA sequence	DNA sequence (2274 bp) Predicted protein sequence (663 aa)
HaloTag ORF Clone	FHC01459
Flexi ORF Clone	FXC01459
Description	ATP-binding cassette sub-family G member 2 (Placenta-specific ATP- binding cassette transporter) (Breast cancer resistance protein) (Mitoxantrone resistance-associated protein) (CD338 antigen) (CDw338).

Features of the cloned cDNA sequence

Description

Length: 2274 bp

Physical map

Restriction map

Prediction of protein coding region (GeneMark analysis) for : cloned DNA seq.

Warning for N-terminal truncation: NO

Warning for coding interruption : NO

Integrity of 3' end

Length of 3'UTR	64 bp
Genome contig ID	gi89161207r_89132346
PolyA signal sequence (CATAAA,-32)	+--------+--------+----*----+---- TCACATAAAAAAGAAGCACTTTGATTGAAGTATTC
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AATCAAGTTTTTTTGTTGTTTTCTGTTCCCTTGCCATCACACTGTTGCAC

Features of the protein sequence

Description

Length: 663 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
XP_526633	99.2	ATP-binding cas...	Pan troglodytes
Q9UNQ0	100.0	ATP-binding cas...	Homo sapiens
AAO14617	99.8	ATP-binding cas...	Homo sapiens
AAQ92941	99.8	mutant ATP-bind...	Homo sapiens
AAC97367	99.8	breast cancer r...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method	interpro_ID	From	To	Entry	Definition
BlastProDom	IPR003439	195	236	PD000006	ABC transporter related
HMMPfam	IPR003439	85	270	PF00005	ABC transporter related
HMMPfam	IPR013525	383	594	PF01061	ABC-2 type transporter
HMMSmart	IPR003593	80	278	SM00382	AAA+ ATPase
ProfileScan	IPR003439	45	294	PS50893	ABC transporter related

Prediction of transmembrane (TM) segments

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	401	QASIAQIIVTVVLGLVIGAIYFG	423	PRIMARY	23
	2	434	RAGVLFFLTTNQCFSSVSAVELF	456	SECONDARY	23
	3	462	LFIHEYISGYYRVSSYFLGKLLS	484	SECONDARY	23
	4	487	LPMRMLPSIIFTCIVYFMLGLK	508	PRIMARY	22
	5	514	FFVMMFTLMMVAYSASSMALAIA	536	PRIMARY	23
	6	548	LMTICFVFMMIFSGLLVNLTTIA	570	PRIMARY	23