ORK04224

Kazusa Clone (Original Type)

Gene/Protein Characteristic Table for ORK04224

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Accession No	AB209461
Product ID	ORK04224
Clone name	ah03580
Vector information	The cDNA fragment was inserted at the SalI-NotI site of the ... The cDNA fragment was inserted at the SalI-NotI site of the pBluescript II SK(+) vector (GenBank Accession No. X52328). The 5' end of the cDNA was repaired and ligated with the SalI adapter (5'TCGACCCACGCGTCCG3') and inserted at the SalI site of the vector. The 3'end of the cDNA was inserted at the NotI site of the vector.
Symbol	ATP7B
cDNA sequence	DNA sequence (5655 bp) Predicted protein sequence (662 aa)
Description	Copper-transporting ATPase 2 (EC 3.6.3.4) (Copper pump 2) (Wilson disease-associated protein).

Features of the cloned cDNA sequence

Description

Length: 5655 bp

Physical map

Restriction map

Prediction of protein coding region (GeneMark analysis) for : cloned DNA seq.

Warning for N-terminal truncation: NO

Warning for coding interruption : YES

Integrity of 3' end

Length of 3'UTR	511 bp
Genome contig ID	gi51511729r_51306382
PolyA signal sequence (None)	+--------+--------+----*----+---- TGCTTTCTTCCTGCATAGTCTGTTCCTTTCTTCGT
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* ACATAGTCTGTTCCTTTTCTCTCCTGTGTGCTTGTCAGTGGGGACCCCTC

Features of the protein sequence

Description

Length: 662 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	Exp	ID%	Protein	Source
BAD92698	0	100.0	ATPase, Cu++ tr...	Homo sapiens
XP_001103242	1.5e-216	92.5	ATPase, Cu++ tr...	Macaca mulatta
AAY41166	1.1e-195	97.2	Wilson's diseas...	Homo sapiens
AAB52902	1.2e-195	97.3	ATP7B [Homo sap...	Homo sapiens
AAI17201	1.4e-195	91.6	ATP7B protein [...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR001757	68	82	PR00119	ATPase
	IPR001757	222	236	PR00119	ATPase
	IPR001757	387	398	PR00119	ATPase
	IPR001757	409	419	PR00119	ATPase
	IPR000695	434	450	PR00120	H+ transporting ATPase
	IPR000695	462	478	PR00120	H+ transporting ATPase
	IPR001757	462	481	PR00119	ATPase
	IPR001757	485	497	PR00119	ATPase
	IPR000695	493	518	PR00120	H+ transporting ATPase
HMMPfam	IPR008250	1	214	PF00122	E1-E2 ATPase-associated region
HMMPfam	IPR005834	218	485	PF00702	Haloacid dehalogenase-like hydrolase
HMMTigr	IPR006403	1	571	TIGR01511	ATPase
	IPR006416	1	570	TIGR01525	Heavy metal translocating P-type ATPase
	IPR001757	29	244	TIGR01494	ATPase
	IPR001757	372	541	TIGR01494	ATPase
ScanRegExp	IPR001757	224	230	PS00154	ATPase

Prediction of transmembrane (TM) segments

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	134	RFSGYFVPFIIIMSTLTLVNPNK	156	PRIMARY	23
	2	158	ISQTEVIIRFAFQTSITVLCIAC	180	SECONDARY	23
	3	184	LGLATPTAVMVGTGVAAQNGILI	206	SECONDARY	23
	4	371	MKGQTAILVAIDGVLCGMIAIAD	393	SECONDARY	23
	5	522	LVLALIYNLVGIPIAAGVFMPIG	544	PRIMARY	23
	6	550	WMGSAAMAASSVSVVLSSLQLK	571	SECONDARY	22