ORK11858

Kazusa Clone (Original Type)

Gene/Protein Characteristic Table for ORK11858

Order Kazusa clone(s) from :

Accession No
Product ID	ORK11858
Clone name	bf00036
Vector information	The cDNA fragment was inserted at the XhoI-SacI site of the ... The cDNA fragment was inserted at the XhoI-SacI site of the pBC SK+ vector(Cm resistance; http://www.kazusa.or.jp/huge/vectorinfo/pbcskp_s.txt) with sequences including attB1 and attB2 sites (CTCGAGCAGC TGAAGCTTTC ACAAGTTTGT ACAAAAAAGC AGGCTCTTC-5' end of cDNA, GAGCTCTCAC CACTTTGTAC AAGAAAGCTG GGCGGCCGCT TTTTTTTTTT TTTTTTT-3' end of cDNA).
Symbol	ATR
cDNA sequence	DNA sequence (8166 bp) Predicted protein sequence (2651 aa)
HaloTag ORF Clone	FHC11858
Flexi ORF Clone	FXC11858
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1)(Ataxia telangiectasia and Rad3-related protein)(FRAP-related protein 1)

Features of the cloned cDNA sequence

Description

Length: 8166 bp

Physical map

Restriction map

Prediction of protein coding region (GeneMark analysis) for : cloned DNA seq.

Warning for N-terminal truncation: NO

Warning for coding interruption : NO

Integrity of 3' end

Length of 3'UTR	193 bp
Genome contig ID	gi89161205r_143550768
PolyA signal sequence (AATAAA,-21)	+--------+--------+----*----+---- TTCAGTTATTAAGAAATAAACTGCTTTCTTAATAC
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* ATACTGTGCATTATAATTGGAGAAATAGAATATCATGTGTTCTTATGGTC

Features of the protein sequence

Description

Length: 2651 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
Q13535	99.9	Serine/threonin...	Homo sapiens
CAA70298	99.9	atr [Homo sapiens].	Homo sapiens
XP_516792	99.6	ataxia telangie...	Pan troglodytes
XP_001112149	98.7	ataxia telangie...	Macaca mulatta
XP_534295	94.8	similar to Seri...	Canis lupus fam...

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR000357	806	842	PF02985	HEAT
	IPR012993	1126	1232	PF08064	UME
	IPR000357	1336	1372	PF02985	HEAT
	IPR003151	1778	2101	PF02259	PIK-related kinase
	IPR000403	2328	2574	PF00454	Phosphatidylinositol 3- and 4-kinase
	IPR003152	2619	2651	PF02260	PIK-related kinase
HMMSmart	IPR012993	1126	1232	SM00802	UME
HMMSmart	IPR000403	2330	2640	SM00146	Phosphatidylinositol 3- and 4-kinase
ProfileScan	IPR000357	812	846	PS50077	HEAT
	IPR014009	1647	2192	PS51189	PIK-related kinase
	IPR000403	2329	2651	PS50290	Phosphatidylinositol 3- and 4-kinase
	IPR003152	2619	2651	PS51190	PIK-related kinase
ScanRegExp	IPR000403	2467	2487	PS00916	Phosphatidylinositol 3- and 4-kinase

Prediction of transmembrane (TM) segments

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	208	NLEFIEVTLLTVLTRIIAIVFF	229	PRIMARY	22
	2	346	SDLLKAALCHLLQYFLKFVPAGY	368	SECONDARY	23
	3	1212	HACLGSLLSHVIVALLPLIHIQP	1234	PRIMARY	23
	4	1529	FKVTIYLLPHILVYVLLGCN	1548	PRIMARY	20