ORK06199

Kazusa Clone (Original Type)

Gene/Protein Characteristic Table for ORK06199

Order Kazusa clone(s) from :

Accession No	AB209118
Product ID	ORK06199
Clone name	hh13729
Vector information	The cDNA fragment was inserted at the SalI-NotI site of the ... The cDNA fragment was inserted at the SalI-NotI site of the pBluescript II SK(+) vector (GenBank Accession No. X52328). The 5' end of the cDNA was repaired and ligated with the SalI adapter (5'TCGACCCACGCGTCCG3') and inserted at the SalI site of the vector. The 3'end of the cDNA was inserted at the NotI site of the vector.
Symbol	NTRK2
cDNA sequence	DNA sequence (5802 bp) Predicted protein sequence (781 aa)
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

Features of the cloned cDNA sequence

Description

Length: 5802 bp

Physical map

Restriction map

Prediction of protein coding region (GeneMark analysis) for : cloned DNA seq.

Warning for N-terminal truncation: NO

Warning for coding interruption : NO

Features of the protein sequence

Description

Length: 781 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
BAD92355	100.0	BDNF/NT-3 growt...	Homo sapiens
Q16620	100.0	BDNF/NT-3 growt...	Homo sapiens
XP_001107014	99.7	neurotrophic ty...	Macaca mulatta
XP_001107330	99.8	neurotrophic ty...	Macaca mulatta
XP_001496485	96.8	neurotrophic ty...	Equus caballus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method	interpro_ID	From	To	Entry	Definition
BlastProDom	IPR000719	590	756	PD000001	Protein kinase
FPrintScan	IPR001245	663	676	PR00109	Tyrosine protein kinase
FPrintScan	IPR001245	712	730	PR00109	Tyrosine protein kinase
HMMPfam	IPR000372	77	106	PF01462	Leucine-rich repeat
	IPR001611	162	184	PF00560	Leucine-rich repeat
	IPR013098	243	329	PF07679	Immunoglobulin I-set
	IPR001245	584	757	PF07714	Tyrosine protein kinase
HMMSmart	IPR000372	77	111	SM00013	Leucine-rich repeat
	IPR000483	194	241	SM00082	Cysteine-rich flanking region
	IPR003599	249	330	SM00409	Immunoglobulin subtype
	IPR003598	255	319	SM00408	Immunoglobulin subtype 2
	IPR001245	584	780	SM00219	Tyrosine protein kinase
	IPR002290	584	781	SM00220	Serine/threonine protein kinase
ProfileScan	IPR007110	243	328	PS50835	Immunoglobulin-like
ProfileScan	IPR000719	584	781	PS50011	Protein kinase
ScanRegExp	IPR000719	590	618	PS00107	Protein kinase
	IPR008266	718	730	PS00109	Tyrosine protein kinase
	IPR002011	746	754	PS00239	Receptor tyrosine kinase

Prediction of transmembrane (TM) segments

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	60	RLWGFCWLVVGFWRAAFACPTSC	82	PRIMARY	23
SOSUI2	2	479	VYAVVVIASVVGFCLLVMLFLLK	501	PRIMARY	23