ORK07126

Kazusa Clone (Original Type)

Gene/Protein Characteristic Table for ORK07126

Order Kazusa clone(s) from :

Accession No	AK226155
Product ID	ORK07126
Clone name	sj03455
Vector information	The cDNA fragment was inserted at the SalI-NotI site of the ... The cDNA fragment was inserted at the SalI-NotI site of the pBluescript II SK(+) vector (GenBank Accession No. X52328). The 5' end of the cDNA was repaired and ligated with the SalI adapter (5'TCGACCCACGCGTCCG3') and inserted at the SalI site of the vector. The 3'end of the cDNA was inserted at the NotI site of the vector.
Symbol	TLR4
cDNA sequence	DNA sequence (4914 bp) Predicted protein sequence (844 aa)
Description	Toll-like receptor 4 precursor (hToll) (CD284 antigen).

Features of the cloned cDNA sequence

Description

Length: 4914 bp

Physical map

Restriction map

Prediction of protein coding region (GeneMark analysis) for : cloned DNA seq.

Warning for N-terminal truncation: NO

Warning for coding interruption : NO

Features of the protein sequence

Description

Length: 844 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
O00206	100.0	Toll-like recep...	Homo sapiens
Q9TTN0	99.6	Toll-like recep...	Pan paniscus
XP_001146983	99.5	similar to toll...	Pan troglodytes
BAG55038	99.3	toll-like recep...	Gorilla gorilla
BAG55037	99.3	toll-like recep...	Pan paniscus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR001611	182	195	PR00019	Leucine-rich repeat
FPrintScan	IPR001611	377	390	PR00019	Leucine-rich repeat
HMMPfam	IPR001611	60	82	PF00560	Leucine-rich repeat
	IPR001611	84	106	PF00560	Leucine-rich repeat
	IPR001611	108	130	PF00560	Leucine-rich repeat
	IPR001611	156	179	PF00560	Leucine-rich repeat
	IPR001611	181	203	PF00560	Leucine-rich repeat
	IPR001611	379	395	PF00560	Leucine-rich repeat
	IPR001611	405	426	PF00560	Leucine-rich repeat
	IPR001611	428	448	PF00560	Leucine-rich repeat
	IPR001611	477	500	PF00560	Leucine-rich repeat
	IPR001611	502	524	PF00560	Leucine-rich repeat
	IPR001611	526	548	PF00560	Leucine-rich repeat
	IPR000483	611	633	PF01463	Cysteine-rich flanking region
	IPR000157	681	819	PF01582	Toll-Interleukin receptor
HMMSmart	IPR003591	62	81	SM00369	Leucine-rich repeat
	IPR003591	82	105	SM00369	Leucine-rich repeat
	IPR003591	106	129	SM00369	Leucine-rich repeat
	NULL	154	178	SM00365	NULL
	IPR003591	154	178	SM00369	Leucine-rich repeat
	IPR003591	179	200	SM00369	Leucine-rich repeat
	NULL	179	200	SM00365	NULL
	IPR003591	206	230	SM00369	Leucine-rich repeat
	IPR003591	377	398	SM00369	Leucine-rich repeat
	NULL	403	425	SM00365	NULL
	NULL	426	447	SM00365	NULL
	IPR003591	426	449	SM00369	Leucine-rich repeat
	IPR003591	475	499	SM00369	Leucine-rich repeat
	NULL	500	521	SM00365	NULL
	IPR003591	500	523	SM00369	Leucine-rich repeat
	IPR003591	524	545	SM00369	Leucine-rich repeat
	IPR000483	584	633	SM00082	Cysteine-rich flanking region
	IPR000157	678	823	SM00255	Toll-Interleukin receptor
ProfileScan	IPR000157	677	823	PS50104	Toll-Interleukin receptor

Prediction of transmembrane (TM) segments

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	643	VLSVLVVSVVAVLVYKFYFHLML	665	PRIMARY	23
SOSUI2	2	705	VPPFQLCLHYRDFIPGVAIAANI	727	SECONDARY	23